Guinea-Bissau will square off with Ghana in their final 2019 Africa Cup of Nations (AFCON) Group F match on Tuesday.
Kick-off is at 18h00 CAT.
The encounter is scheduled to be played at the Suez Stadium in the Egyptian city of Suez.
The African Wild Dogs held Benin to a 0-0 draw in their second group match which was played in Ismailia on Saturday.
Guinea-Bissau can only advance to the knockout stages for the first time if they overcome Ghana and the results in other groups go their way.
Baciro Cande, the Guinea-Bissau head coach, will be looking to guide the African Wild Dogs to a big win over Ghana.
Meanwhile, Ghana drew 0-0 with Cameroon in their second group match which was played in Ismailia on Saturday.
The Black Stars will progress to the round of 16 if they secure a victory against a stubborn Guinea-Bissau side.
Ghana head coach Kwesi Appiah will be hoping to lead his side to their first victory in Egypt against the African Wild Dogs.
This will be he first-ever match between Guinea-Bissau and Ghana.